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Luradox 40mg Tablet 1 Strip
Luradox is used in the treatment of:
- Schizophrenia
- Depressive episodes associated with Bipolar I Disorder
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✅ Description:
Although the precise mechanism by which Lurasidone exerts its effects in schizophrenia and bipolar depression is not fully known, its clinical benefit is thought to involve antagonism of central dopamine D2 and serotonin 5-HT2A receptors.
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✔️ Dosage and Administration
Luradox must be taken with food containing at least 350 calories, as this significantly enhances its absorption.
✔️ For Schizophrenia:
Starting dose: 40 mg once daily.
No initial titration is necessary.
Maximum recommended dose: 160 mg daily.
✔️ For Bipolar Depression (Bipolar I Disorder):
Starting dose: 20 mg once daily, either as monotherapy or in combination with lithium or valproate.
No initial titration is required.
Maximum recommended dose (monotherapy or adjunct): 120 mg daily.
✔️ Pediatric Use:
Safety and efficacy in children and adolescents have not been established.
✔️ Adverse Effects
Frequent side effects may include:
- Drowsiness
- Akathisia (restlessness)
- Extrapyramidal symptoms (motor control disturbances)
- Nausea
✔️ Drug Interactions
Concurrent use with potent CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir) or strong CYP3A4 inducers (e.g., rifampin, phenytoin, carbamazepine) is not advised due to potential alteration in drug levels.
✔️ Contraindications
Lurasidone is contraindicated in individuals with known hypersensitivity to the drug or its components. It must not be used with strong CYP3A4 inhibitors or inducers
✔️ Pregnancy & Lactation
- Pregnancy Category B: Animal studies have not demonstrated fetal risk, but there are no adequate studies in pregnant women.
- Lactation: Lurasidone is present in breast milk. Due to the potential for serious harm to nursing infants, the benefits of continued treatment should be weighed against the risk, and a decision should be made to either discontinue the drug or stop breastfeeding.
✔️ Precautions
- Not approved for dementia-related psychosis; use may increase the risk of death in elderly patients.
- May elevate the risk of suicidal ideation and behavior in adolescents and young adults.
✔️ Storage:
Keep in a cool, dry place at or below 30°C. Protect from light.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
